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» Dose finding studies and cross-over trialsFeb 24, 09:00 AM

Here are some notes on cross-over trials and within-patient titration in indirect assays.

» Evidence-based medicine and clinical diagnosisFeb 23, 10:07 AM

I just started reading The evidence base of clinical diagnosis, edited by J. André Knottnerus and Frank Buntinx (Wiley, 2009, 2nd ed.).

» Exploratory data mining and data cleaningFeb 17, 11:49 AM

I just got my copy of Exploratory Data Mining and Data Cleaning, by Dasu and Johnson (Wiley, 2003).

» Winter desk cleaningFeb 10, 11:29 AM

Some of the latest news from

» Hierarchical Omega coefficientFeb 10, 11:18 AM

While browsing questions related to psychometrics posted late in 2012 on Cross Validated, I noticed two questions dealing with hierarchical ωh.

» Cognitive diagnosis modelsDec 10, 10:41 AM

As its name suggests, a cognitive diagnosis model aims at "diagnosing" which skills examinees have or do not have. It has become very popular in recent years because it overcomes standard limitations of summated scale scores derived from classical test or item response theory.

» Dicing with death -- Chance, risk and healthDec 9, 11:40 AM

I just finished reading a very nice book from Stephen Senn: Dicing with death. Chance, Risk and Health (Cambridge University Press, 2003). It is very nicely written; I am no expert in English but I found that the quality of the writing gives a special sense to statistical issues discussed in this book.

» Testlet response theoryAug 27, 11:27 AM

Here is a brief overview of Testlet Response Theory and its Applications, by Wainer, Bradlow, and Wang (Cambridge University Press, 2007).

» Methods for handling treatment switchesJul 5, 05:56 PM

In a recent statistical seminar I attended, there was a discussion on statistical strategies to cope with treatment switching and the estimation of survival.

» Mendelian randomizationJun 15, 06:52 PM

Some time ago, I proposed a paper on Mendelian randomisation for the Journal Club on Cross Validated. Apparently, it fell to the water, but here are the main ideas from that paper.

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