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Statistical questions in evidence-based medicine

April 4, 2014

Statistical questions in evidence-based medicine was written long ago by Martin Bland and Janet Peacock (Oxford University Press, 2000), but is is still full of good recommendations. It is a series of case-based questions and answers.

It is supposed to serve as a companion to An introduction to Medical Statistics. I personally bought the third edition of Indrayan’s Medical Biostatistics, which I find very good, and I just ordered Medical Statistics in Clinical and Epidemiological Research, by Marit B. Veierød, Stian Lydersen and Petter Laake.

A related book is: Peacock, J and Kerry, S (2007). Presenting medical statistics. From proposal to publication. Oxford University Press.

Here is a brief sketch of the book. The second chapter asks basic questions about study design, emphasizing the role of randomized controlled trials as a gold standard in evidence-based medicine. The third chapter is about observational studies when no intervention or treatment takes place (cross-sectional, cohort and case-control) and various sources of bias that can arise as a result of the way subjects are included in the study. See this old post of mine to get an overview of this kind of studies and their biases. Chapters 4 and 5 are concerned with summarizing and presenting data. There’s no mention of ICMJE guidelines (more recently, the SAMPL guidelines).

Other articles of interest are listed below:

Here are some things I don’t like in Statistical questions in evidence-based medicine:

See Also

» Workflow for statistical data analysis » Statistical learning and regression » Regression Methods in Biostatistics » Twenty canonical questions in machine learning » Do a large amount of consulting